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Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer's disease

✍ Scribed by D. Allan Butterfield; H. Fai Poon; Daret St. Clair; Jeffery N. Keller; William M. Pierce; Jon B. Klein; William R. Markesbery


Book ID
113811944
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
573 KB
Volume
22
Category
Article
ISSN
0969-9961

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## Abstract Alzheimer's disease (AD) is the most common form of dementia and is pathologically characterized by senile plaques, neurofibrillary tangles, synaptic disruption and loss, and progressive neuronal deficits. The exact mechanism(s) of AD pathogenesis largely remain unknown. With advances i