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Redox factor 1 (Ref-1) enhances specific DNA binding of p53 by promoting p53 tetramerization

✍ Scribed by Hanson, Sven; Kim, Ella; Deppert, Wolfgang


Book ID
110069412
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
250 KB
Volume
24
Category
Article
ISSN
0950-9232

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We previously reported that two nuclear factor 1-like elements mediated the transcription of the rat p53 gene. A 40-kDa protein was shown to bind to these elements, which was different from common NF1 family proteins. In this study, the biochemical properties of the 40-kDa binding protein were inves