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Redifferentiation of dedifferentiated human articular chondrocytes: comparison of 2D and 3D cultures

✍ Scribed by M.M.J. Caron; P.J. Emans; M.M.E. Coolsen; L. Voss; D.A.M. Surtel; A. Cremers; L.W. van Rhijn; T.J.M. Welting


Book ID
119305006
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
867 KB
Volume
20
Category
Article
ISSN
1063-4584

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## Abstract During monolayer culture, articular chondrocytes dedifferentiate into fibroblast‐like cells. The mechanisms underlying this process are poorly understood. We sought to further characterize dedifferentiation by identifying an extended panel of genes that distinguish articular cartilage f