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Redefining the Role of Retinoic Acid in Limb Development

✍ Scribed by Kawakami, Yasuhiko

Book ID
123580086
Publisher
Elsevier
Year
2013
Tongue
English
Weight
59 KB
Volume
3
Category
Article
ISSN
2211-1247

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Perturbation of retinoic acid (RA)-mediated limb development suggests a role for diminished RA signaling in the teratogenesis of ethanol
✍ Corey S. Johnson; Robert M. Zucker; Edward Sidney Hunter III; Kathleen K. Sulik πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 510 KB

## Abstract ## BACKGROUND: A proposed mechanism for ethanol teratogenicity entails ethanol‐mediated reductions in retinoic acid (RA). This premise was investigated utilizing a mouse model, with limb reduction defects as the teratogenic end point. ## METHODS: Ethanol, Disulfiram, or BMS‐189453 wa