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Red fluorescent scaffold for highly sensitive protease activity probes

✍ Scribed by Yu Kushida; Kenjiro Hanaoka; Toru Komatsu; Takuya Terai; Tasuku Ueno; Kengo Yoshida; Masanobu Uchiyama; Tetsuo Nagano

Book ID
113496913
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
539 KB
Volume
22
Category
Article
ISSN
0960-894X

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## Abstract A new rhodamineβ€…B‐based fluorescent probe for the hypochlorite anion (OCl^βˆ’^) has been designed, synthesized, and characterized. The probe comprises a spectroscopic unit of rhodamineβ€…B and an OCl^βˆ’^‐specific reactive moiety of dibenzoylhydrazine. The probe itself is nearly nonfluorescen