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Recyclization of Hydrazides of 2-Carboxyphenyldifurylmethanes: Synthesis of Novel 4,10-Dihydro-3H-pyridazino[1,6-b]isoquinolin-10-one System.

✍ Scribed by Alexander V. Butin; Artem S. Dmitriev; Vladimir T. Abaev; Valery E. Zavodnik

Book ID
102004710
Publisher
John Wiley and Sons
Year
2007
Weight
26 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract On treatment with lead tetraacetate (Pb(OAc)~4~), the 1‐(alkylidene)‐1,2,3,4‐tetrahydro‐__N__‐(trichloroacetyl)isoquinolines **2a**–**2c** as well as the tribromoacetyl derivative **4** undergo an oxidative cyclization with concomitant migration of the trihalogenomethyl group to afford