Recurrent primary pleomorphic adenomas of salivary gland origin : Intrasurgical rupture, histopathologic features, and pseudopodia
✍ Scribed by Gert Henriksson; Karl Magnus Westrin; Bengt Carlsöö; Claes Silfverswärd
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 110 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
were reviewed. All patients alive in April 1995 (n Å 230) were sent a simple questionnaire. Two hundred thirteen of these patients received follow-up. All cases of tumor recurrence after surgery or intrasurgical rupture of the tumor capsule were reviewed histopathologically.
Results
. Two (7.1%) of the 28 patients who had macroscopic capsule rupture during surgery experienced recurrence at a later stage. This was not a statistically higher rate than the 4.1% recurrence rate for the rest of the material. As many as 5 of the 9 primary tumors that subsequently recurred (56%) sent fingerlike tumor extensions or pseudopodia outside the pseudocapsule. The rate of occurrence of such structures was statistically higher than that of the tumors that ruptured during surgery (25%) and the examined uncomplicated cases (8%).
CONCLUSIONS.
Occurrence of pseudopodia-microscopic fingerlike formations of tumor tissue that extend beyond the main lump of the tumor-is a significant risk factor for local recurrence.