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Recurrent pneumomediastinum and pneumothorax in Langerhans cell histiocytosis

✍ Scribed by Yule, S. M.; Hamilton, J.R. L.; Windebank, K. P.

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 288 KB
Volume: 29
Category: Article
ISSN: 0098-1532
DOI: 10.1002/(sici)1096-911x(199708)29:2<139::aid-mpo13>3.0.co;2-a

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✦ Synopsis

Pneumothorax is an unusual complication of pulmonary Langerhans cell histiocytosis. We report three children who developed recurrent intrathoracic air leaks. In one case, bilateral pneumothoraces may have been precipated by intermittent positive pressure ventilation during general anaesthesia. Chemical pleurodesis was unsuccessful in preventing recurrence of pneu-mothoraces in two children. The use of extracorporeal membrane oxygenation as an alternative to intermittent positive pressure ventilation in children with respiratory failure from Langerhans cell histiocytosis is discussed.

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