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Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia

✍ Scribed by Bergmann, Anke K.; Schneppenheim, Sina; Seifert, Marc; Betts, Matthew J.; Haake, Andrea; Lopez, Cristina; Maria Murga Penas, Eva; Vater, Inga; Jayne, Sandrine; Dyer, Martin J.S.; Schrappe, Martin; Dührsen, Ulrich; Ammerpohl, Ole; Russell, Robert B.; Küppers, Ralf; Dürig, Jan; Siebert, Reiner


Book ID
121836691
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
441 KB
Volume
53
Category
Article
ISSN
1045-2257

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## Abstract T‐cell prolymphocytic leukemia (T‐PLL) is a rare malignant proliferation of lymphoid cells with a postthymic phenotype. Previous cytogenetic and molecular studies reported complex karyotypes with recurrent chromosomal abnormalities, including translocations involving either __TCL1__ at