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Recurrent hepatic lymphangiomatosis after orthotopic liver transplantation

✍ Scribed by Seong H. Ra; Robert F. Bradley; Michael C. Fishbein; Ronald W. Busuttil; David S.K. Lu; Charles R. Lassman

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 453 KB
Volume: 13
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.21306

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✦ Synopsis

Hepatic lymphangiomatosis is a rare disease characterized by an abnormal lymphatic proliferation involving the liver alone, liver and spleen, or multiple organs. Hepatic lymphangiomatosis becomes symptomatic secondary to compression or replacement of the normal parenchyma, which can lead to liver failure. Resection and orthotopic liver transplantation (OLT) can be used as treatment for this disease. We herein describe a 42-year-old female who had undergone successful OLT for hepatic lymphangiomatosis with recurrent disease detected 19 yr later in the transplanted liver. This is, to our knowledge, the first described case of recurrent hepatic lymphangiomatosis after OLT. In conclusion, we discuss the clinical, radiologic, pathologic, and immunohistochemical findings and review other reported cases of hepatic lymphangiomatosis that have undergone OLT.

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