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Recurrent adult nephroblastoma long-term remission after surgery plus adjuvant high-dose chemotherapy, radiation therapy, and allogeneic bone marrow transplantation

✍ Scribed by Pierre S. Hupperets; Miek G. Havenith; Geert H. Blijham


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
361 KB
Volume
69
Category
Article
ISSN
0008-543X

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✦ Synopsis


The authors report a case of Stage IV, unfavorable histologic type adult nephroblastoma. The patient was treated with multimodal therapy: combination chemotherapy consisting of cyclophosphamide, doxorubicin, cisplatin, and etoposide succeeded by nephrectomy and radiation therapy. After a disease-free period of 27 months, a pararectal relapse was treated by surgery, high-dose chemotherapy, and allogeneic bone marrow transplantation (BMT). The patient is alive and disease-free 3.5 years after BMT.