Recurrences after irradiation in early vocal cord cancer with literature review

✍ Scribed by B. Jose; David L. Calhoun; Alyas Mohammed

• Book ID: 102439470
• Publisher: John Wiley and Sons
• Year: 1984
• Tongue: English
• Weight: 256 KB
• Volume: 27
• Category: Article
• ISSN: 0022-4790
• DOI: 10.1002/jso.2930270405

✦ Synopsis

Radiation therapy in early glottic cancer offers an excellent cure rate with preservation of voice. This study is an analysis of 25 (18%) patients who had failures after irradiation. Ten patients were in stage I (TINoMo) and 15 patients in stage I1 (T2NoMo). All patients received megavoltage irradiation with an average dose of 6600 rad, 180 to 200 rad per day, 5 days in a week. Of the failures, 15 patients had the tumor controlled by salvage surgery, laryngectomy being the most common surgical procedure. The median time to recurrence was 23 months. A detailed analysis of the failures, along with a literature review, is done in this paper.