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Recurrence risks for autosomal, epistatic two-locus systems: The effects of linkage disequilibrium

โœ Scribed by Trojak, Joseph E. ;Murphy, Edmond A. ;Opitz, John M.


Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
519 KB
Volume
9
Category
Article
ISSN
0148-7299

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The autosomal dominant cerebellar ataxias (ADCA) are clinically and genetically heterogeneous. To date, several loci (SCAI-V) have been identified for ADCA type I. We have studied two large families from the northern part of The Netherlands with ADCA type I with a broad intra-familial variation of s