with complete responses were given an additional course of chemotherapy (intra-School of Medicine, Nagasaki, Japan. arterial cisplatin and doxorubicin) and irradiation (20 Gy), and patients with resid-
Recurrence and treatment of urinary bladder cancer after failure in radiotherapy
β Scribed by Eeva Salminen
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 492 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0008-543X
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β¦ Synopsis
One hundred fifty-five patients with urinary bladder cancer who were not suitable for radical surgery were treated with full-course radiotherapy, 6600 cGy in 9 weeks, split-course. After the treatment recurrences were observed in 94 patients (SO%), 49 (53%) were treated with transurethral surgery and intravesical cytostatics, local surgery, systemic cytostatics, or palliative radiotherapy. The median survivals for the patients were 33,10,4, and 2.4 months, respectively. The outcome of treatment for radiotherapy failures was related to the nature of the failure, ureteric obstruction, the recurrence rate, and the mode of treatment. Shrinkage of the bladder was observed in 15 patients (16%). The occurrence of bladder shrinkage was related to the increase in frequency of recurrences and of different types of treatments.
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The effect of the radiosensitizer razoxane was prospectively evaluated in advanced and recurrent gastric cancer. Endpoints of the study were mainly palliation, local response rates, and achievement of local control. From 1984 to 1993, razoxane (Rz) was given together with radiation therapy (R") to 2
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