Synthesis and characterization of the fi
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Yoshiaki Yanai; Kazuhiro Irie; Hajime Ohigashi; Paul A. Wender
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Article
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1997
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Elsevier Science
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English
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The first cysteine-rich domains (CRD's) of mouse PKCq and PKC/~ (~I-CRDI and 6-CRD1) were prepared by automated solid phase peptide synthesis. In the presence of phosphatidylsenne, zinc-folded ~I-CRD 1 did not bind [-SH]phorlx)l 12,13-dibutyrate (PDBu) at all while the zinc-folded second CRD of mous