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Recovery of sensitivity to acetylcholine following desensitization in muscles of different vertebrate species

✍ Scribed by F. Vyskočil


Publisher
Springer
Year
1975
Tongue
English
Weight
384 KB
Volume
361
Category
Article
ISSN
0031-6768

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Skeletal muscles of adult mice and frogs were dissociated enzymatically and prepared for patchclamping within less than 6 h. Outside-out patches were superfused with repetitive pulses of acetylcholine (ACh) with switching times of about 0.2 ms. Peak responses were reached within 1 ms. In mouse muscl