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Recovery of cortical acetylcholine output after ganglioside treatment in rats with lesion of the nucleus basalis

✍ Scribed by Florian, A.; Casamenti, F.; Pepeu, G.

Book ID
123289104
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
243 KB
Volume
75
Category
Article
ISSN
0304-3940

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GM1 ganglioside facilitates the recovery
GM1 ganglioside facilitates the recovery of high-affinity choline uptake in the cerebral cortex of rats with a lesion of the nucleus basalis magnocellularis
✍ F. Pedata; L. Giovannelli; G. Pepeu πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 417 KB

The effect of repeated administrations of GM 1 monosialoganglioside on highaffinity choline uptake (HACU) was investigated in the cerebral cortex of rats with a unilateral electrolytic lesion of the nucleus basalis magnocellularis. In saline-treated rats, 4 days after lesion, a 38% and 14% decrease