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Recovery of bulky DNA adducts by the regular and a modified 32P-postlabelling assay; influence of the DNA-isolation method

✍ Scribed by Katalin Kovács; Lívia Anna; Péter Rudnai; Bernadette Schoket

Book ID
116759885
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
433 KB
Volume
721
Category
Article
ISSN
1383-5718

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P-Postlabeling is a widely applied assay for the analysis of carcinogen-DNA adducts. Optimization of most steps in this assay has been given attention, but influences of DNA isolation and DNA purity on adduct quantitation have not been investigated systematically. In this study, DNA was isolated fro