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Recovery from a DNA-damage-induced G2 arrest requires Cdk-dependent activation of FoxM1

✍ Scribed by Alvarez-Fernández, Mónica; Halim, Vincentius A; Krenning, Lenno; Aprelia, Melinda; Mohammed, Shabaz; Heck, Albert J; Medema, René H

Book ID: 118675525
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 378 KB
Volume: 11
Category: Article
ISSN: 1469-221X
DOI: 10.1038/embor.2010.46

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## Abstract Multiple myeloma (MM) is a malignancy characterized by the accumulation of tumoral plasma cells in bone marrow. This disease remains incurable and the development of new therapeutic strategies is urgently required. We have studied the effects of 2 selective estrogen receptor disrupters