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Reconstitution of the DNA base excision—repair pathway

✍ Scribed by Grigory Dianov; Tomas Lindahl


Book ID
114317436
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
906 KB
Volume
4
Category
Article
ISSN
0960-9822

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## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the

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✍ Dianov, Grigory 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 154 KB