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Reconstitution of archaeal ribonuclease P from RNA and four protein components

✍ Scribed by Yoshiaki Kouzuma; Masashi Mizoguchi; Hisanori Takagi; Hideo Fukuhara; Masayo Tsukamoto; Tomoyuki Numata; Makoto Kimura


Book ID
117054109
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
341 KB
Volume
306
Category
Article
ISSN
0006-291X

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## Abstract Ribonucleoproteins (RNP) are involved in many essential processes in life. However, the roles of RNA and protein subunits in an RNP complex are often hard to dissect. In many RNP complexes, including the ribosome and the Group II introns, one main function of the protein subunits is to

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## Abstract Ribonuclease P (RNase P) is a ribonucleoprotein (RNP) complex that catalyzes the metal‐dependent maturation of the 5β€² end of precursor tRNAs (pre‐tRNAs) in all organisms. RNase P is comprised of a catalytic RNA (P RNA), and at least one essential protein (P protein). Although P RNA is t