Coordinated downregulation of the antige
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Jose María Romero; Pilar Jiménez; Teresa Cabrera; José Manuel Cózar; Susana Pedr
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Article
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2004
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John Wiley and Sons
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French
⚖ 327 KB
👁 1 views
Downregulation of MHC class I expression is a widespread phenomenon used by tumor cells to escape antitumor T-cell-mediated immune responses. These alterations may play a role in the clinical course of the disease. The aim of our study was to investigate the molecular mechanism underlying the absenc