RECOMBINANT α2-INTERFERON TREATMENT IN CHILDREN WITH CHRONIC HEPATITIS B
✍ Scribed by La Banda, Faustino; Moreno, MercedesRuiz; Carreño, Vincente; Bartolome, Javier; Gutiez, Julia; Y Cajal, SantiagoRamon; Moreno, Alberto; Mora, Ignacio; Porres, JuanCarlos
- Book ID
- 122387402
- Publisher
- The Lancet
- Year
- 1988
- Tongue
- English
- Weight
- 174 KB
- Volume
- 331
- Category
- Article
- ISSN
- 0140-6736
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Twelve children with chronic non-A, non-B hepatitis were entered in a pilot trial of recombinant interferon-alpha. Although all the children had hepatitis C virus RNA in serum, only five had antibodies against this virus. Children received 3 MU/m2 body surface area interferon-alpha 3 times/wk for 6
We have investigated the efficacy of a relatively prolonged course of recombinant leukocyte interferon treatment in 14 chronic HBsAg-, HBeAg-, hepatitis B virus DNA-and DNA polymerasepositive carriers. a-Interferon was administered for 9 weeks. Six of 14 treated carriers have a sustained loss of HBe