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Recombinant versus plasma-derived hepatitis B vaccines: issues of safety, immunogenicity and cost-effectiveness

✍ Scribed by J. Stephenne

Book ID
119150205
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
550 KB
Volume
6
Category
Article
ISSN
0264-410X

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A hepatitis B vaccine produced in yeast by recombinant DNA technology was evaluated using 5-micrograms and 10-micrograms doses in a randomized trial lasting 7 months in 110 male armed forces recruits aged 17-19 years. Results were compared to those of an identical trial of a plasma-derived vaccine.