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Recombinant tumor necrosis factor and intepleukin-1 both stimulate human synovial cell arachidonic acid release and phospholipid metabolism

✍ Scribed by Richard W. Godfrey; William J. Johnson; Sylvia T. Hoffstein


Book ID
115760206
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
405 KB
Volume
142
Category
Article
ISSN
0006-291X

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Monocyte/macrophage polypeptides (monokines) alter the properties of synovial cells. This interaction could explain some of the properties of the inflamed synovium in rheumatic disease. Only recently has it been possible to test the action of purified monokines on the target synovial cells. We repor