𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Recombinant soluble glypican 3 protein inhibits the growth of hepatocellular carcinoma in vitro

✍ Scribed by Mingqian Feng; Heungnam Kim; Yen Phung; Mitchell Ho


Publisher
John Wiley and Sons
Year
2010
Tongue
French
Weight
398 KB
Volume
128
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis


other bacterial components is a distinct possibility. These observations were confirmed in a very similar study in Finland, 10 and a recent meta-analysis, 11 where the summary risk of lung cancer was 0.62 (0.52-0.75) for agricultural workers. The relative risk of lung cancer was below 1.0 for most subgroups defined according to sex, study design, outcome, smoking adjustment and geographic area. These high-quality studies add weight to the hypothesis that occupational exposure to endotoxin in agriculture is protective against lung cancer and could thus pave the way to further preventive strategies.


πŸ“œ SIMILAR VOLUMES


Soluble glypican 3 inhibits the growth o
✍ Sandra I. Zittermann; Mariana I. Capurro; Wen Shi; Jorge Filmus πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 695 KB

## Abstract The heterogeneity of the molecular pathology of HCC poses a formidable obstacle to the development of non‐cytotoxic therapies. Several pro‐tumorigenic signaling pathways can be aberrantly activated in HCC, including those triggered by Wnts. Glypican‐3 (GPC3), a membrane‐bound heparan su

The oncogenic effect of sulfatase 2 in h
✍ Jin-Ping Lai; Abdul M. Oseini; Catherine D. Moser; Chunrong Yu; Sherine F. Elsaw πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 630 KB

Heparan sulfate proteoglycans (HSPGs) act as coreceptors or storage sites for growth factors and cytokines such as fibroblast growth factor and Wnts. Glypican 3 (GPC3) is the most highly expressed HSPG in hepatocellular carcinoma (HCC). Sulfatase 2 (SULF2), an enzyme with 6-O-desulfatase activity on

Targeting mitogen-activated protein kina
✍ Matthew Hennig; Michele T. Yip-Schneider; Sabrina Wentz; Huangbing Wu; S. K. Hek πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 692 KB

Hepatocellular carcinoma (HCC) is a common cause of death from solid organ malignancy worldwide. Extracellular signal-regulated/mitogen-activated protein kinase kinase (MEK) signaling is a critical growth regulatory pathway in HCC. Targeting MEK with a novel small molecule inhibitor, PD0325901, may