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Recombinant single chain immunotoxins specific for the EGF receptor and ErbB-2

✍ Scribed by Mathias Schmidt; Nancy E. Hynes; Bernd Groner; Winfried Wels


Book ID
116167822
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
133 KB
Volume
31
Category
Article
ISSN
0959-8049

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## Overexpression of the ErbB2 and epidermal growth factor receptor (EGFR) tyrosine kinases is frequently observed in squamous cell carcinomas of the head and neck, and has been correlated with shorter overall survival. By immunoblot analysis, we have found EGFR and ErbB2 expression in 6 out of 6 e