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Recombinant retrovirus-derived virus-like particle-based vaccines induce hepatitis C virus-specific cellular and neutralizing immune responses in mice

✍ Scribed by Huret, Christophe; Desjardins, Delphine; Miyalou, Mathilde; Levacher, Béatrice; Amadoudji Zin, Martin; Bonduelle, Olivia; Combadière, Béhazine; Dalba, Charlotte; Klatzmann, David; Bellier, Bertrand

Book ID
121750058
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
781 KB
Volume
31
Category
Article
ISSN
0264-410X

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## Abstract ## Background The expression of Moloney murine leukemia virus (Mo‐MLV) gag proteins is sufficient to generate retrovirus‐like particles (retroVLPs) that can be used as antigen‐display platforms by pseudotyping with heterologous envelope proteins or by insertion of epitopes in structura