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Recombinant interleukin-1 receptor antagonist protein prevents sensitization and intestinal anaphylaxis in Guinea pigs

✍ Scribed by Vassilia Theodorou; Jean Fioramonti; Lionel Bueno


Book ID
118346032
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
356 KB
Volume
53
Category
Article
ISSN
0024-3205

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Objective. To determine the efficacy of local human interleukin-1 receptor antagonist (HuIL-1Ra) gene therapy in murine collagen-induced arthritis (CIA). Methods. DBN1 mice were immunized against bovine type I1 collagen. Before the onset of arthritis, NIH/3T3 fibroblasts transfected with pMFG-IRAP