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Recombinant human soluble tumor necrosis factor (TNF) receptor (p75) fusion protein Enbrel in patients with refractory hematologic malignancies

✍ Scribed by Apostolia-Maria Tsimberidou; Deborah Thomas; Susan O'Brien; Michael Andreeff; Razelle Kurzrock; Michael Keating; Maher Albitar; Hagop Kantarjian; Francis Giles

Book ID
105991659
Publisher
Springer
Year
2002
Tongue
English
Weight
95 KB
Volume
50
Category
Article
ISSN
0344-5704

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## Abstract Etanercept is a recombinant human soluble tumor necrosis factor (TNF‐α) receptor fusion protein that inhibits TNF‐α, a major mediator in the pathogenesis of graft‐versus‐host disease (GVHD). The purpose of our study was to evaluate the safety and efficacy of etanercept therapy in 21 pat