Both interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) are powerful stimulators of bone resorption in vivo and in vitro. Interleukin-1 receptor antagonist (IL-1ra) binds to many interleukin-1 receptors. It does not activate the receptor and effectively blocks the action of IL-1 alp
Recombinant human interleukin-1 receptor antagonist protects mice against acute doxorubicin-induced cardiotoxicity
β Scribed by Jinzhou Zhu; Jing Zhang; Di Xiang; Zhonghui Zhang; Lin Zhang; Mingyuan Wu; Shunying Zhu; Ruiyan Zhang; Wei Han
- Book ID
- 113588856
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 922 KB
- Volume
- 643
- Category
- Article
- ISSN
- 0014-2999
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Benzyl alcohol, an antimicrobial preservative, accelerates aggregation and precipitation of recombinant human interleukin-1 receptor antagonist (rhIL-1ra) in aqueous solution. The loss of native monomer during incubation at 378C was determined by analysis of sample aliquots with size exclusion high