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Recombinant Human IGF-1 (Insulin-Like Growth Factor) Therapy: Where Do We Stand Today?

✍ Scribed by Bharti Balhara; Madhusmita Misra; Lynne L. Levitsky


Book ID
107599216
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
102 KB
Volume
79
Category
Article
ISSN
0019-5456

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## Abstract The insulin‐like growth factors (IGFs) are potent mitogens for breast cancer cells and their activity is modulated by high affinity binding proteins (IGFBPs). We have recently shown that IGFBP‐1 purified from human amniotic fluid neutralizes IGF‐I‐dependent growth of MCF‐7 cells. In thi