Recombinant human growth hormone downregulated mRNA expression of acute phase proteins induced by IL-1β and IL-6 in hep G2 cell line

INTERLEUKIN-6-INDUCED PRODUCTION OF TYPE

INTERLEUKIN-6-INDUCED PRODUCTION OF TYPE II ACUTE PHASE PROTEINS AND EXPRESSION OF junB GENE ARE DOWNREGULATED BY HUMAN RECOMBINANT GROWTH HORMONE IN VITRO

✍ Beata Derfalvi; Peter Igaz; Kristof A Fulop; Csaba Szalai; Andras Falus 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 222 KB

## Abstract Growth hormone (GH), given therapeutically in many human diseases, is able to modulate the maturation and function of many cells of immune system. The present study demonstrates the effect of human recombinant GH on the production of acute phase proteins (APP) as well as on the gene exp