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Recombinant Hepatitis B Virus Surface Antigen Formulated with B-Type CpG Oligodeoxynucleotide Induces Therapeutic Immunity Against Hepatitis B Virus Surface Antigen-Expressing Liver Cancer Cells in Mice

✍ Scribed by Zhou, Xiaojing; Wei, Hongfei; Sun, Peng; Wu, Xiuli; Wan, Min; Zhang, Peng; Guo, Sheng; Zhao, Tiesuo; Yu, Yongli; Wang, Liying

Book ID: 111645683
Publisher: Mary Ann Liebert
Year: 2012
Tongue: English
Weight: 589 KB
Volume: 27
Category: Article
ISSN: 1084-9785
DOI: 10.1089/cbr.2011.1127

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## Abstract We previously showed that hepatitis B surface antigen (HBsAg)‐producing transgenic mice were more sensitive to hepatocarcinogens than their normal littermates were. We have now investigated the regulation of hepatitis B virus (HBV) gene expression in carcinogen‐induced liver tumors of H