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Recombinant haemagglutinin protein of highly pathogenic avian influenza A (H5N1) virus expressed in Pichia pastoris elicits a neutralizing antibody response in mice

✍ Scribed by Murugan, Subathra; Ponsekaran, Santhakumar; Kannivel, Lingaraja; Mangamoori, Lakshmi Narasu; Chandran, Dev; Villuppanoor Alwar, Srinivasan; Chakravarty, Chandrani; Lal, Sunil K.


Book ID
122483416
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
670 KB
Volume
187
Category
Article
ISSN
0166-0934

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## Abstract The hemagglutinin (HA) of influenza A virus plays an essential role in mediating the entry of the virus into host cells. Here, recombinant full‐length HA5 protein from a H5N1 isolate (A/chicken/hatay/2004(H5N1)) was expressed and purified from the baculovirus‐insect cell system. As expe