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Recombinant GnRH-p53 protein sensitizes breast cancer cells to 5-fluorouracil-induced apoptosis in vitro and in vivo

✍ Scribed by Lu, Yi; Zhang, Zhisong; Yan, Zhenwen; Chen, Li; Deng, Weimin; Lotze, Michael; Wang, Zhou; Lin, Xinli; Li, Lu-Yuan


Book ID
125355681
Publisher
Springer
Year
2013
Tongue
English
Weight
525 KB
Volume
18
Category
Article
ISSN
1360-8185

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## Abstract The availability of oral precursors of 5‐Fluorouracil (5‐FU) and its favorable results in treating advanced breast cancer have renewed the interest in the molecular mechanisms underlying its cytotoxicity. We have compared the changes in cell cycle and cell death parameters induced by 2