Recombinant bone morphogenetic protein-2 induces up-regulation of vascular endothelial growth factor and interleukin 6 in human pre-osteoblasts: Role of reactive oxygen species

Recombinant human bone morphogenetic pro

Recombinant human bone morphogenetic protein-2 enhances expression of interleukin-6 and transforming growth factor-β1 genes in normal human osteoblast-like cells

✍ Dr. Ming H. Zheng; David J. Wood; Stan Wysocki; John M. Papadimitriou; Elizabet 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 777 KB

The process of recombinant human bone morphogenetic protein-2 (rhBMP-2)induced endochondral ossification involves 1 ) the proliferation and differentiation of mesenchymal cells into chondroblasts and osteoblasts; 2) the production and maturation of cartilage and bone matrix; and 3 ) the differentiat