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Recombinant baculoviruses as expression vectors for insect and mammalian cells

✍ Scribed by Thomas A Kost; J Patrick Condreay


Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
86 KB
Volume
10
Category
Article
ISSN
0958-1669

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✦ Synopsis


Baculovirus expression vectors are widely used for expressing heterologous proteins in cultured insect cells. Recent advances include further development of the system for production of multi-subunit protein complexes, co-expression of protein-modifying enzymes to improve heterologous protein production, and additional applications of baculovirus display technology. The application of modified baculovirus vectors for gene expression in mammalian cells continues to expand.


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