𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Recombinant adenovirus-mediated p14ARF overexpression sensitizes human breast cancer cells to cisplatin

✍ Scribed by Xiyun Deng; Min Kim; Didier Vandier; Yun-jin Jung; Toshiki Rikiyama; Magda K Sgagias; Merrill Goldsmith; Kenneth H Cowan

Book ID
117052412
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
182 KB
Volume
296
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Overexpression of bax sensitizes human b
Overexpression of bax sensitizes human breast cancer MCF-7 cells to radiation-induced apoptosis
✍ Chouhei Sakakura; Elizabeth A. Sweeney; Tsutomu Shirahama; Yasuyuki Igarashi; Se 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 553 KB

Resistance to apoptosis plays an important role in tumors that are refractory to chemotherapy and ionizing radiation (IR). bax, which forms a heterddimer with bcl-2 and accelerates apoptosir, is not, or only weakly. expremed in most human breast cancer cells, and weak bax expression is considered to

Drug-resistant human bladder-cancer cell
Drug-resistant human bladder-cancer cells are more sensitive to adenovirus-mediated wild-type p53 gene therapy compared to drug-sensitive cells
✍ Toshiro Shirakawa; Ryohei Sasaki; Thomas A. Gardner; Chinghai Kao; Zhu-Jun Zhang 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 373 KB

We investigated the therapeutic potential and molecular mechanism of adenovirus-mediated wt p53 gene therapy for drug-resistant human bladder cancers. KK47, a human bladder-cancer cell line, along with the drug-resistant sublines KK47/DDP10, KK47/DDP20 (cisplatin-resistant) and KK47/ ADM (doxorubici

Inhibition of farnesyl protein transfera
Inhibition of farnesyl protein transferase sensitizes human MCF-7 breast cancer cells to roscovitine-mediated cell cycle arrest
✍ Józefa Węsierska-Gądek; Margarita Maurer; Gerald Schmid 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 253 KB 👁 1 views

## Abstract We reported recently that roscovitine (ROSC), a selective cyclin‐dependent kinase (CDK) inhibitor, arrests human MCF‐7 breast cancer cells in G~2~ phase of the cell cycle, and concomitantly induces apoptosis. Human MCF‐7 breast cancer cells are known to express elevated levels of c‐Ha‐R