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Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice

✍ Scribed by Song, S; Goudy, K; Campbell-Thompson, M; Wasserfall, C; Scott-Jorgensen, M; Wang, J; Tang, Q; Crawford, J M; Ellis, T M; Atkinson, M A

Book ID
110039452
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
177 KB
Volume
11
Category
Article
ISSN
0969-7128

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## Abstract ## Background Increased efficiency of transgene expression is desired for virus‐mediated gene delivery. In the present study, we examined the effect of calcium phosphate (CaPi) on recombinant adeno‐associated virus (rAAV)‐mediated insulin therapy in diabetic animals. ## Methods The r