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Recognition of structural perturbations in DNA by human DNA(cytosine-5)methyltransferase

✍ Scribed by Baker, David J.; Kan, Julie L.C.; Smith, Steven S.

Book ID
123385215
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
361 KB
Volume
74
Category
Article
ISSN
0378-1119

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## Abstract We have developed a facile procedure for the purification of DNA methyltransferase activity from human placenta. The procedure avoids the isolation of nuclei and the dialysis and chromatography of large volumes. A purification of 38,000‐fold from the whole cell extract has been achieved