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Recognition of novel objects and their location in rats with selective cholinergic lesion of the medial septum

✍ Scribed by Li Cai; Robert B. Gibbs; David A. Johnson


Book ID
116773746
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
363 KB
Volume
506
Category
Article
ISSN
0304-3940

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## Abstract To lesion the cholinergic input to the hippocampus, rats received injections of 192 IgG‐saporin into the medial septum/vertical limb of the diagonal band (MS/VDB). The lesions produced near‐total loss of choline acetyltransferase (ChAT)‐positive neurons in the MS/VDB. The loss was accom