Recognition of molecularly imprinted polymers for a quaternary alkaloid of berberine
โ Scribed by Chia-Yun Chen; Chih-Hung Wang; Arh-Hwang Chen
- Book ID
- 116905051
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 780 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0039-9140
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## Abstract Molecularly imprinted polymers (MIPs) have been prepared from methacrylic acid (MAA) and ethylene glycol dimethacrylate (EGDMA) as the functional monomer and crosslinker, respectively, for cholecystokinin C terminal pentapeptide (CCKโ5), and screened for their rebinding characteristics.
Micro-contact imprinting has been used to form thin-film molecular imprints of ovalbumin (OVA) in polymers supported on glass slides. Thermocalorimetric data was used to optimise the choice of functional monomer and cross-linker to maximise selectivity and minimise non-specific recognition. A polyme