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Recognition of guanine and adenine in DNA by cytosine and thymine containing peptide nucleic acids (PNA)

โœ Scribed by Egholm, Michael; Nielsen, Peter E.; Buchardt, Ole; Berg, Rolf H.


Book ID
118015697
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
264 KB
Volume
114
Category
Article
ISSN
0002-7863

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Gradient-corrected density functional computations with triplezeta-type basis sets were performed to determine the preferred protonation site and the absolute gas-phase proton affinities of the most stable tautomer of the ลฝ . ลฝ . ลฝ . ลฝ . DNA bases thymine T , cytosine C , adenine A , and guanine G .