Recognition of ephedrine enantiomers by molecularly imprinted polymers designed using a computational approach
β Scribed by Piletsky, S. A.; Karim, K.; Piletska, E. V.; Turner, A. P. F.; Day, C. J.; Freebairn, K. W.; Legge, C.
- Book ID
- 125501718
- Publisher
- Royal Society of Chemistry
- Year
- 2001
- Tongue
- English
- Weight
- 207 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0003-2654
- DOI
- 10.1039/B102426B
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Micro-contact imprinting has been used to form thin-film molecular imprints of ovalbumin (OVA) in polymers supported on glass slides. Thermocalorimetric data was used to optimise the choice of functional monomer and cross-linker to maximise selectivity and minimise non-specific recognition. A polyme
## Abstract A simplified computational model was proposed to simulate the synthesis of molecularly imprinted polymers (MIP), removal of template and recognition of the template and its analogues by MIP. The MIPs with nicotinamide and isoβnicotinamide as templates were prepared using methacrylic aci