𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Recognition in molecularly imprinted polymer α2-adrenoreceptor mimics

✍ Scribed by Johanna Berglund; Ian A. Nicholls; Christer Lindbladh; Klaus Mosbach

Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
325 KB
Volume
6
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.

✦ Synopsis

Molecularly imprinted polymers (MIPs) selective for the ct2-adrenoreceptor antagonist yohimbine (1) have been prepared and studied as ot2-adrenoreceptor mimics. Marked ligand stereoselectivity was demonstrated in radioligand binding and HPLC studies upon comparison to blank and corynanthine (2) MIPs. K D values in the nanomolar range have been shown for ant/-1 MIP prepared in chloroform solutions upon rebinding in organic media.

📜 SIMILAR VOLUMES

Metal ion mediated recognition in molecu
Metal ion mediated recognition in molecularly imprinted polymers
✍ Jun Matsui; Ian A. Nicholls; Toshifumi Takeuchi; Klaus Mosbach; Isao Karube 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 639 KB

Molecularly imprinted polymer metal-chelate antibody combining site mimics have been used to examine the roles of metal ion and ligand shape on binding selectivity. Chromatography based recognition studies highlight the utility of metal ion coordination for controlling molecularly imprinted polymer

Novel chiral recognition elements for mo
Novel chiral recognition elements for molecularly imprinted polymer preparation
✍ Malin Knutsson; Håkan S. Andersson; Ian A. Nicholls 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 59 KB 👁 2 views

The use of a novel chiral functional monomer system in molecular imprinting protocols is described. The monomer, dibenzyl (2R,3R)-O-monoacryloyl tartrate, possesses a hydroxyl moiety which can be used to direct template-functional monomer interactions during molecular imprinting polymerization. This

Selective recognition of ovalbumin using
Selective recognition of ovalbumin using a molecularly imprinted polymer
✍ Wei-Xiang Su; John Rick; Tse-Chuan Chou 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 936 KB

Micro-contact imprinting has been used to form thin-film molecular imprints of ovalbumin (OVA) in polymers supported on glass slides. Thermocalorimetric data was used to optimise the choice of functional monomer and cross-linker to maximise selectivity and minimise non-specific recognition. A polyme

Study of the nature of recognition in mo
Study of the nature of recognition in molecularly imprinted polymers
✍ Håkan S. Andersson; Ann-Christin Koch-Schmidt; Sten Ohlson; Klaus Mosbach 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 743 KB

In the present study molecularly imprinted polymers (MIPS) were prepared against a series of structurally related compounds containing various numbers of pyridyl groups. The goal, to increase understanding of the mechanisms of recognition in MIPS, was achieved by comparing the patterns of retention