Recognition highlights: Toll-like receptors
β Scribed by David S. Goodsell
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 178 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0952-3499
- DOI
- 10.1002/jmr.778
No coin nor oath required. For personal study only.
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During infection or tissue damage, the innate immune system detects and responds to nucleic acids released from pathogens or damaged host cells. Accumulating evidence has showed that specific sequences, modifications or structures of nucleic acids influence their immunomodulatory activities. Resulti
## Abstract Toll like receptors (TLRs) are βpattern recognition proteinsβ that discriminate between self and nonβself. They interact with products of infectious agents to activate cells of the innate immune system and also stimulate the adaptive immune system. Intracellular and extracellular TLRs r