## Abstract Nanoparticles provide large surface areas and controlled surface functionality and structure, making them excellent scaffolds for peptide recognition. A family of nanoparticles has been fabricated by amino acid functionalization to afford tailored surfaces. These particles are complemen
✦ LIBER ✦
Recognition and Stabilization of Peptide α-Helices Using Templatable Nanoparticle Receptors
✍ Scribed by Verma, Ayush; Nakade, Hiroshi; Simard, Joseph M.; Rotello, Vincent M.
- Book ID
- 127196001
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 102 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0002-7863
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## Abstract A series of 14 residue amphipathic α‐helical peptides, in which the sidechains of glutamic acid and lysine have been covalently joined, was synthesized in order to determine the effect of spacing, position and orientation of these lactam bridges. It was found that although an (__i__, __