✦ LIBER ✦

Reciprocal modulation between TH17 and other helper T cell lineages

✍ Scribed by Yujing Bi; Guangwei Liu; Ruifu Yang

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 121 KB
Volume: 226
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.22331

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✦ Synopsis

Abstract

T helper 17 (TH17) cells have well‐described roles in autoimmune disease. However, TH17 is not stable in some physiological or pathological courses. Also, TH17 cells can reciprocally modulate and convert into other helper T cell subpopulations. The fully exploring the reciprocal regulatory effects and its immunoregulatory mechanisms are becoming interesting topics in the immunological study. In this review, we summarized reciprocal modulation pattern between TH17 cell and other helper T cell subpopulations in the mouse model of autoimmune diseases and human diseases. J. Cell. Physiol. 226: 8–13, 2010. © 2010 Wiley‐Liss, Inc.

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