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Reciprocal DNA topoisomerase II cleavage events at 5′-TATTA-3′ sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing

✍ Scribed by Whitmarsh, Ryan J; Saginario, Charles; Zhuo, Ya; Hilgenfeld, Eva; Rappaport, Eric F; Megonigal, Maureen D; Carroll, Martin; Liu, Mingli; Osheroff, Neil; Cheung, Nai-Kong V


Book ID
110068136
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
398 KB
Volume
22
Category
Article
ISSN
0950-9232

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